Causally upstream of, negative effect: Difference between revisions
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== Review Status == | == Review Status == | ||
Last reviewed: | Last reviewed: February 8, 2023 | ||
Reviewed by: Cristina Casals, Marc Feuermann, Pascale Gaudet, David Hill, Patrick Masson, Paul Thomas, Kimberly Van Auken | |||
[http://wiki.geneontology.org/index.php/Annotation_Relations Back to: Annotation Relations] | [http://wiki.geneontology.org/index.php/Annotation_Relations Back to: Annotation Relations] |
Revision as of 09:29, 8 February 2023
Overview and Scope of Use
- This relation is used in GO-CAMs but not in standard annotation extensions.
- This relation is intended to represent a negative causal effect of one activity on another, where the mechanism is not known.
- The 'causally upstream of, negative effect' relation is used to relate two GO Molecular Functions when:
- the mechanism that relates the upstream molecular function to the downstream molecular function is not understood
- the upstream molecular function occurs before the downstream molecular function
- the upstream molecular function has a negative effect on the downstream molecular function
Annotation Usage Guidelines
- What to capture
- Relationships between molecular functions when a negative effect has been demonstrated but the mechanism is not known.
- What not to capture
- Relationships where the mechanism is known. These should be represented by other relationships.
Examples
- TBD
Ontology Usage Guidelines
This relation is not used in the ontology.
Relations Ontology
causally upstream of, negative effect
Review Status
Last reviewed: February 8, 2023
Reviewed by: Cristina Casals, Marc Feuermann, Pascale Gaudet, David Hill, Patrick Masson, Paul Thomas, Kimberly Van Auken