Causally upstream of, positive effect: Difference between revisions

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* GO-CAM Annotation
* GO-CAM Annotation
** What to capture
** What not to capture
**Usage Examples
**Usage Examples
***A peptidase activity that processes a signaling ligand.  
***A peptidase activity that processes a signaling ligand.  

Revision as of 10:12, 2 November 2022

Overview and Scope of Use

  • The 'causally upstream of, positive effect' relation is used to relate GO Biological Processes (BP) and/or GO Molecular Functions (MF) when:
    • the mechanism that relates the upstream process (BP or MF) to the downstream process (BP or MF) is understood
    • the activities of the gene products in the upstream process occur before events in the downstream process
    • in order for the downstream process to occur normally, the upstream process needs to occur
  • Domain- Domain refers to the ontology terms that can be further specified with the relation.
    • Any biological process
    • Any molecular function
  • Range- Range describes the ontology terms that can be used to further specify the domain using the relation.
    • Any biological process
    • Any molecular function

Annotation Usage Guidelines

  • Standard Annotation
    • What to capture
    • What not to capture
    • Usage Examples
      • This relation should not be used for conventional annotations. To capture this information, curators should create a GO_CAM model in the Noctua tool.

Ontology Usage Guidelines

  • This relation is not used in the ontology.


Quality Control Checks

  • Annotations can be validated using a Shape Expressions (ShEx) representation of allowed relations between ontology terms.

Child Terms

Cross Reference to Relation Ontology (RO)

causally upstream of, positive effect

Review Status

Reviewed on Nov 2, 2022 DavidH


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