Causally upstream of, positive effect

Overview

• The 'causally upstream of, positive effect' relation is used to relate GO Biological Processes (BP) and/or GO Molecular Functions (MF) when:
  • the mechanism that relates the upstream process (BP or MF) to the downstream process (BP or MF) is understood
  • the activities of the gene products in the upstream process occur before events in the downstream process
  • in order for the downstream process to occur normally, the upstream process needs to occur

Examples of Usage

• A peptidase activity that processes a signaling ligand.
  • http://noctua.geneontology.org/editor/graph/gomodel:632cf60a00000039

Quality Control Checks

• Annotations can be validated using a Shape Expressions (ShEx) representation of allowed relations between ontology terms.

Relations Ontology

causally upstream of, positive effect

Review Status

Modified on Sept 26, 2022 Last Reviewed: November 26, 2018

Back to: Annotation Relations