Provides input for: Difference between revisions
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== Overview == | == Overview and Scope of Use== | ||
*The 'directly provides input for' relation is used to relate two GO Molecular Functions when: | *The 'directly provides input for' relation is used to relate two GO Molecular Functions when: | ||
**Two Molecular Functions succeed one another directly | **Two Molecular Functions succeed one another directly | ||
**The output of the first molecular function is an input of the second Molecular Function. | **The output of the first molecular function is an input of the second Molecular Function. | ||
* Domain: Domain refers to the ontology terms that can be further specified with the relation. | |||
** GO Molecular Functions | |||
* Range: Range describes the ontology terms that can be used to further specify the domain using the relation. | |||
** GO Molecular Functions | |||
The 'directly provides input for' relation is most commonly used between successive steps of a metabolic pathway. | The 'directly provides input for' relation is most commonly used between successive steps of a metabolic pathway. | ||
| Line 24: | Line 28: | ||
* This relation is not used in the ontology. | * This relation is not used in the ontology. | ||
== Quality Control Checks == | == Quality Control Checks == | ||
Revision as of 10:24, 2 November 2022
Overview and Scope of Use
- The 'directly provides input for' relation is used to relate two GO Molecular Functions when:
- Two Molecular Functions succeed one another directly
- The output of the first molecular function is an input of the second Molecular Function.
- Domain: Domain refers to the ontology terms that can be further specified with the relation.
- GO Molecular Functions
- Range: Range describes the ontology terms that can be used to further specify the domain using the relation.
- GO Molecular Functions
The 'directly provides input for' relation is most commonly used between successive steps of a metabolic pathway.
Annotation Usage Guidelines
- Standard Annotation
- 'directly provides input for' should not be used for conventional annotations. Instead its use should be reserved for GO-CAM models.
- GO-CAM Annotation
- 'directly provides input' should be reserved to related successive Molecular Functions in GO-CAM models.
- Usage Examples
- In glycolysis, triose phosphate isomerase activity (MF) 'directly provides input for' glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (MF).
- triose phosphate isomerase activity converts dihydroxyacetone phosphate (input) to glyceraldehyde-3-phosphate (output) as part of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase converts glyceraldehyde-3-phosphate (input) to 3-phosphonato-D-glyceroyl phosphate(4−) (output).
- http://noctua.geneontology.org/editor/graph/gomodel:632cf60a00000208
- A glucose tansmembrane transporter activity (MF) 'directly provides input for' lactose synthase activity (MF).
- cytosolic glucose (input) is transported across the Golgi membrane to become Golgi-lumenal glucose (output). In the Golgi lumen the Golgi-lumenal glucose (input) is converted into lactose (output).
- http://noctua.geneontology.org/editor/graph/gomodel:632cf60a00000239?
- In glycolysis, triose phosphate isomerase activity (MF) 'directly provides input for' glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (MF).
Ontology Usage Guidelines
- This relation is not used in the ontology.
Quality Control Checks
- Shex
- https://github.com/geneontology/go-shapes/blob/master/shapes/go-cam-shapes.shex
- Search this file for 'directly_provides_input_for'.
Child Terms
Cross Reference to the Relation Ontology (RO)
Review Status
Reviewed: May 11, 2018
Reviewed: September 27, 2022 DavidH
Reveiwed: October 26, 2022 DavidH