GO-CAM Conference Call - 2019-07-16

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Call Information

  • See GO's Google calendar for Zoom URL
  • email Kimberly if you need access to the GO's Google calendar


GO-CAM Specifications

  • One of the most frequently asked questions about GO-CAM modeling is: what relation(s) can/should I use in my model?
  • To address this, and other aspects of GO-CAM modeling and Noctua development, a small group has been working on shoring up specifications for GO-CAM models.
  • This will impact:
    • Manual GO-CAM (and conventional) curation
    • MOD imports
    • Reactome imports
    • Tool development
    • Model validation, inference explanations, and other QC checks
  • We'd like to discuss several aspects of this ongoing work today.

GO-CAM Specification Proposal


  • Much of the specifications involves relations between individuals/nodes in a GO-CAM model and the cardinality of their use
  • Since Molecular Functions/Activities are at the core of GO-CAM models, we've been looking at the Annotation Extensions relations used for conventional MF annotations to make sure they align with the specifications
  • The current use of MF annotation extensions relations is in this Google spreadsheet that we will review on today's call
  • As we work through the specifications, we are reviewing and updating wiki documentation on use of Annotation Relations


  • On call: Bob, Chris, Colin, David, Dmitry, Dustin, Edith, Elena, Giulia, Harold, Helen, Karen, Kevin, Kimberly, Laurent-Philippe, Li, Midori, Pascale, Petra, Ruth, Sabrina, Suzi