GO-CAM Working Group Call 2018-06-26

Meeting URL

https://stanford.zoom.us/j/976175422

Agenda

Logistics

• User accounts
  • Follow-up from last week: Sandy L
  • https://github.com/geneontology/noctua/issues/563
    • Closed - all okay
• Groups
  • https://github.com/geneontology/noctua-models/issues/96
    • Should this be discussed on Wednesday's technical call?

Noctua

• Landing Page (under development)
  • Browsing GO-CAMs
  • User and Group Pages
  • Curators should look around the landing page, provide feedback
    • Can now search using a PMID
    • Green paper icons beneath model titles; mouse over shows paper data
    • One question about presentation of author name(s) - first? last?

Documentation

• Noctua tool
• Annotation relations

Proposal for this group

• Focus on specific, commonly used curation modules
  • For example, transcription, signaling pathways, metabolic pathways
• Groups will annotate papers of their own choosing
• We will discuss representation of the data in GO-CAMs, and any questions or issues that arise
  • Choosing the appropriate relation
  • Assigning evidence
• Give feedback to tool developers, ontology editors based on our discussions
  • Github trackers
    • noctua
    • simple annoton editor
    • go-ontology
• Develop additional documentation

Curation Project(s) for this Group

• Will try creating models for papers that describe transcriptional regulation
• A caveat to this is that right now the MF branch for transcription factors is still under review, so we may have to make some changes to annotations in the future
  • However, it would still be good to work out the relations between the MFs and the BPs wrt transcription and upstream and downstream activities and processes
• Google doc for entering papers and curation questions
  • Sabrina - PMID:28687631 'Clock1a affects mesoderm development and primitive hematopoiesis by regulating Nodal-Smad3 signaling in the zebrafish embryo.'
  • Kimberly - PMID: 28578929 'Morphological Diversity of C. elegans Sensory Cilia Instructed by the Differential Expression of an Immunoglobulin Domain Protein.'

Minutes

• On call: Dave F, Giulia, Harold, Kimberly, Laurent-Philippe, Pascale, Penelope, Sabrina, Sandy, Seth, Stacia