Enables: Difference between revisions

Revision as of 14:01, 11 May 2018

Overview

The 'enables' relation is used to relate a gene or gene product to a GO Molecular Function, e.g. MAPK1 enables protein kinase activity. This indicates that the MAPK1 gene product executes the protein kinase activity..

Definition

Child Terms

Examples of Usage

In gene annotation files, the 'enables' relation is used for associations between a gene or gene product and a Molecular Function. 'enables' is considered the default relation between a gene or gene product and a Molecular Function.

Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1.
- The paper demonstrates that NEDD4 'enables' a ubiquitin-protein ligase activity
Examplar: http://noctua.berkeleybop.org/editor/graph/gomodel:5323da1800000002
- Inferred GPAD: http://noctua.berkeleybop.org/workbench/annpreview/?model_id=gomodel:5323da1800000002

Quality Control Checks

Relations Ontology

enables

Review Status

Last reviewed: May 11, 2018

Back to: Annotation Relations

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 == Examples of Usage ==
-*In gene annotation files, the 'enables' relation is used for all associations between a gene or gene product and a Molecular Function.
+*In gene annotation files, the 'enables' relation is used for associations between a gene or gene product and a Molecular Function.  'enables' is considered the default relation between a gene or gene product and a Molecular Function.
 *[https://www.ncbi.nlm.nih.gov/pubmed/17996703 Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1.]