Enables

Overview

The 'enables' relation is used to relate a gene or gene product to a GO Molecular Function, e.g. MAPK1 enables protein kinase activity. This indicates that the MAPK1 gene product executes the protein kinase activity.

Examples of Usage

• In gene annotation files, the 'enables' relation is used for associations between a gene or gene product and a Molecular Function. 'enables' is considered the default relation between a gene or gene product and a Molecular Function.

• Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1.
  • The paper demonstrates that NEDD4 'enables' a ubiquitin-protein ligase activity
• Examplar: http://noctua.berkeleybop.org/editor/graph/gomodel:5323da1800000002
  • Inferred GPAD: http://noctua.berkeleybop.org/workbench/annpreview/?model_id=gomodel:5323da1800000002

Relations Ontology

enables

Review Status

Last reviewed: May 11, 2018

Back to: Annotation Relations