Heart Development workshop (Archived): Difference between revisions

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Zebrafish mutants affecting several aspects of heart tube development and morphogenesis - '''[http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&dopt=AbstractPlus&term=16319113 PMID:16319113]'''
Zebrafish mutants affecting several aspects of heart tube development and morphogenesis - '''[http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&dopt=AbstractPlus&term=16319113 PMID:16319113]'''
Review of Zebrafish heart development, covers L/R patterning, morphogenesis - '''[http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&dopt=AbstractPlus&term=19371733 PMID:16319113]'''


== Notes ==
== Notes ==

Revision as of 16:19, 2 June 2009

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Please suggest agenda items, relevant papers and other information relating to heart development GO terms that you would like discussed at this workshop, to enable us to form an agenda.


Participants

BHF-UCL GO annotators

Dr Varsha Khodiyar

Dr Ruth Lovering


GO Editors

Dr Tanya Berardini

Dr David Hill

Dr Doug Howe


Heart Development Experts

Professor Shumo Bhattacharya

Professor Pete Scambler

Dr Ross Breckenridge

Dr Paul Riley

Programme

Location - 4th Floor seminar room, Rayne Institute map

Timing - 9am - 6pm

A detailed agenda will be posted closer to the meeting.


Current Heart Development Ontology Terms

The currently available heart development process ontology can be viewed here chart (May 2009)

The 38 GO IDs used to create this graph:

GO:0001947 GO:0003007 GO:0007507 GO:0007510 GO:0007512 GO:0007513 GO:0010002 GO:0035050 GO:0035051 GO:0035052 GO:0035053 GO:0035054 GO:0042684 GO:0042685 GO:0048738 GO:0048739 GO:0055003 GO:0055004 GO:0055005 GO:0055006 GO:0055007 GO:0055008 GO:0055009 GO:0055010 GO:0055011 GO:0055012 GO:0055014 GO:0055015 GO:0055017 GO:0060038 GO:0060214 GO:0060317 GO:0060347 GO:0060379 GO:0060411 GO:0060412 GO:0060413 GO:0060419


heart morphological structure development (18 terms) chart:

GO:0001947 GO:0003007 GO:0007507 GO:0007512 GO:0035050 GO:0035054 GO:0048738 GO:0048739 GO:0055008 GO:0055009 GO:0055010 GO:0055017 GO:0060214 GO:0060347 GO:0060411 GO:0060412 GO:0060413 GO:0060419


differentiation of specific cardiac cell types (20 terms) chart:

GO:0007510 GO:0007513 GO:0010002 GO:0035051 GO:0035052 GO:0035053 GO:0042684 GO:0042685 GO:0055003 GO:0055004 GO:0055005 GO:0055006 GO:0055007 GO:0055011 GO:0055012 GO:0055014 GO:0055015 GO:0060038 GO:0060317 GO:0060379

Suggested Agenda Items

  • Development of primary and secondary heart fields (Doug)
  • morphogenic and migratory changes to those cell populations as they move towards formation of the heart tube (Doug)
  • L/R patterning (Doug)
  • cardiac muscle cell specification/differentiation/development (Doug)
  • development of the electrical signaling systems of the heart (Doug)
  • neural crest contribution to the heart (David)


Relevant papers

Recent review on signaling involved in development of the second heart field - PMID:19390062

Differences in cardiomyocyte differentiation b/t mice and zebrafish - PMID:19395641

Zebrafish mutants affecting several aspects of heart tube development and morphogenesis - PMID:16319113

Review of Zebrafish heart development, covers L/R patterning, morphogenesis - PMID:16319113

Notes

1. Cardiac muscle cell development was covered by the muscle group, but it won't hurt to give it a review (David)

2. In GO, heart does indeed refer to the dorsal vessel of arthropods, but I'm not sure we will have time to cover it in this meeting other than to make sure we are not inconsistent with the representation of its development (David)