Is active in: Difference between revisions

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*In gene annotation files, the 'is active in' relation is used for associations between a gene or gene product and a Cellular Component.
*In gene annotation files, the 'is active in' relation is used for associations between a gene or gene product and a Cellular Component.


*[https://www.ncbi.nlm.nih.gov/pubmed/17996703 Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1.]
*https://www.ncbi.nlm.nih.gov/pubmed/8654923 The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease.]
**The paper demonstrates that NEDD4 'enables' a ubiquitin-protein ligase activity
**The paper shows that ced-3 localizes to the cytosol
* Examplar: http://noctua.berkeleybop.org/editor/graph/gomodel:5323da1800000002
* Examplar: http://noctua.berkeleybop.org/editor/graph/gomodel:593423e000000013
** Inferred GPAD: http://noctua.berkeleybop.org/workbench/annpreview/?model_id=gomodel:5323da1800000002
** Inferred GPAD:http://noctua.berkeleybop.org/workbench/annpreview/?model_id=gomodel:593423e000000013


== Quality Control Checks ==
== Quality Control Checks ==

Revision as of 14:13, 11 May 2018

Overview

The 'is active in' relation is used to relate a gene or gene product to the GO Cellular Component in which the gene or gene product enables its Molecular Function, e.g. ced-3 'is active in' cytosol. This indicates that the ced-3 gene product executes its molecular function in the cytosol.

Definition

Child Terms

Examples of Usage

  • In gene annotation files, the 'is active in' relation is used for associations between a gene or gene product and a Cellular Component.

Quality Control Checks

Relations Ontology

enables

Review Status

Last reviewed: May 11, 2018

Back to: Annotation Relations