Is active in: Difference between revisions

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== Overview ==
== Overview ==
The 'is active in' relation is used to relate a gene or gene product to the GO Cellular Component in which the gene or gene product enables its Molecular Function, e.g. ced-3 'is active in' cytosol.  This indicates that the ced-3 gene product executes its molecular function in the cytosol.
The 'is active in' relation is used to relate a gene or gene product to the GO Cellular Component in which the gene or gene product enables its Molecular Function, e.g. ced-3 'is active in' cytosol.  This indicates that the ced-3 gene product executes its molecular function in the cytosol.
=== Definition ===
=== Child Terms ===


== Examples of Usage ==
== Examples of Usage ==
*In gene annotation files, the 'is active in' relation is used for associations between a gene or gene product and a Cellular Component.
*In gene annotation files, the 'is active in' relation is used for associations between a gene or gene product and a Cellular Component.


*[https://www.ncbi.nlm.nih.gov/pubmed/17996703 Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1.]
== Relations Ontology ==
**The paper demonstrates that NEDD4 'enables' a ubiquitin-protein ligase activity
[http://www.ontobee.org/ontology/RO?iri=http://purl.obolibrary.org/obo/RO_0002432 is active in]
* Examplar: http://noctua.berkeleybop.org/editor/graph/gomodel:5323da1800000002
** Inferred GPAD: http://noctua.berkeleybop.org/workbench/annpreview/?model_id=gomodel:5323da1800000002


== Quality Control Checks ==
== Property Chains ==
 
* (enables o occurs in) subPropertyOf is active in
== Relations Ontology ==
[http://www.ontobee.org/ontology/RO?iri=http://purl.obolibrary.org/obo/RO_0002327 enables]


== Review Status ==
== Review Status ==
 
Last reviewed: April 5, 2020
Last reviewed: May 11, 2018


[http://wiki.geneontology.org/index.php/Annotation_Relations Back to: Annotation Relations]
[http://wiki.geneontology.org/index.php/Annotation_Relations Back to: Annotation Relations]
[[Category: Annotation]]
[[Category: Relations]]
[[Category: Gene Product to Term Relations]]






[[Category: Gene Product to Term Relations]]
[[Category: Gene Product to Term Relations]]

Latest revision as of 06:49, 9 February 2023


Overview

The 'is active in' relation is used to relate a gene or gene product to the GO Cellular Component in which the gene or gene product enables its Molecular Function, e.g. ced-3 'is active in' cytosol. This indicates that the ced-3 gene product executes its molecular function in the cytosol.

Examples of Usage

  • In gene annotation files, the 'is active in' relation is used for associations between a gene or gene product and a Cellular Component.

Relations Ontology

is active in

Property Chains

  • (enables o occurs in) subPropertyOf is active in

Review Status

Last reviewed: April 5, 2020

Back to: Annotation Relations

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