Manager Call 2017-02-15: Difference between revisions

From GO Wiki
Jump to navigation Jump to search
Line 25: Line 25:
*How much do we need to coordinate this work with ontology development, specifically the molecular function refactoring and design patterns?
*How much do we need to coordinate this work with ontology development, specifically the molecular function refactoring and design patterns?
*Can we come up with a plan and propose it to the consortium?
*Can we come up with a plan and propose it to the consortium?
*[https://github.com/geneontology/go-annotation/issues/1532 Val's regulation and causality]


[[Category: GO Managers Meetings]]
[[Category: GO Managers Meetings]]

Revision as of 12:14, 15 February 2017

Bluejeans URL

Agenda

GOC Meeting in June

  • Curators have asked for more information about Reactome workshop in order to make their travel plans
  • Who will contact Pankaj and Peter for that and report back to the group?

Protege Workshop in Berkeley Next Week

  • What else needs to be done for prep/planning?

Annotation Conference Call

  • Some big issues facing the annotation group
  • Addition of new qualifiers/relations was thought to be desired and important for several annotation streams - conventional, PAINT, LEGO
  • However, the questions of which ones to use and how to apply the ones we do use consistently are still open
  • We need a good way to coordinate annotation work to make sure we actually get some useful guidelines
  • One suggestion - divide up curators to look at specific areas of biology to generate guidelines for that area
    • There's a lot of value in what Val has done for the cell cycle, but would guidelines for cell cycle apply to development, behavior, metabolic processes?
      • For example, what is the relation between a transcription factor required for specification of a particular neuron, and the behaviors mediated by that neuron?
    • PAINT view of annotations can be very informative here
    • LEGO models will help here as well
  • Other possibilities - examine genes that are annotated to both a process and regulation of that process
  • Are the autophagy and apoptosis projects models for this work?
  • Should part of this work also include a systematic analysis of what changes result from using different annotation sets in enrichment analysis?
  • How much do we need to coordinate this work with ontology development, specifically the molecular function refactoring and design patterns?
  • Can we come up with a plan and propose it to the consortium?