Manager Call 2017-02-15: Difference between revisions
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*How much do we need to coordinate this work with ontology development, specifically the molecular function refactoring and design patterns? | *How much do we need to coordinate this work with ontology development, specifically the molecular function refactoring and design patterns? | ||
*Can we come up with a plan and propose it to the consortium? | *Can we come up with a plan and propose it to the consortium? | ||
*[https://github.com/geneontology/go-annotation/issues/1532 Val's regulation and causality] | |||
[[Category: GO Managers Meetings]] | [[Category: GO Managers Meetings]] |
Revision as of 12:14, 15 February 2017
Bluejeans URL
Agenda
GOC Meeting in June
- Curators have asked for more information about Reactome workshop in order to make their travel plans
- Who will contact Pankaj and Peter for that and report back to the group?
Protege Workshop in Berkeley Next Week
- What else needs to be done for prep/planning?
Annotation Conference Call
- Some big issues facing the annotation group
- Addition of new qualifiers/relations was thought to be desired and important for several annotation streams - conventional, PAINT, LEGO
- However, the questions of which ones to use and how to apply the ones we do use consistently are still open
- We need a good way to coordinate annotation work to make sure we actually get some useful guidelines
- One suggestion - divide up curators to look at specific areas of biology to generate guidelines for that area
- There's a lot of value in what Val has done for the cell cycle, but would guidelines for cell cycle apply to development, behavior, metabolic processes?
- For example, what is the relation between a transcription factor required for specification of a particular neuron, and the behaviors mediated by that neuron?
- PAINT view of annotations can be very informative here
- LEGO models will help here as well
- There's a lot of value in what Val has done for the cell cycle, but would guidelines for cell cycle apply to development, behavior, metabolic processes?
- Other possibilities - examine genes that are annotated to both a process and regulation of that process
- Are the autophagy and apoptosis projects models for this work?
- Should part of this work also include a systematic analysis of what changes result from using different annotation sets in enrichment analysis?
- How much do we need to coordinate this work with ontology development, specifically the molecular function refactoring and design patterns?
- Can we come up with a plan and propose it to the consortium?