Manager Call 2017-07-05

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Joining the Call on Zoom

https://stanford.zoom.us/j/754529609

Agenda

From June 21st Call

Licensing

Attributes in Noctua Annotations

New Issues

Signaling Project and Cambridge Meeting

  • Project strategy
    • We have an annotation call on next Tuesday, July 11th and we should have a (proposed) strategy in place for that call
  • Recent review article: http://www.cellsignallingbiology.org/csb/002/002.pdf
    • Divide each ~two-week period into specific annotation and ontology issues
      • For example, first week would be annotation of ligands (and receptors)
    • Make sure we strike the right balance between:
      • theoretical (relations between MFs, BPs; representation in the ontology)
      • practical (consistent annotations; annotation guidelines that reflect experiments reported in the literature)
    • Review and flag all existing github tickets in ontology and annotation repositories
      • Add signaling label to annotation repository (one exists already in ontology)
  • Cambridge meeting, Sunday, October 1st
    • Any funding available for non GO-funded groups?

GO AGR Slim

Annotation Qualifiers

  • What are the next steps?
    • Add guidelines to github documentation with examples for use of each BP qualifier (include positive and negative directionality)
    • Propose a half-day online working group meeting for this
      • acts_upstream_of_or_within
      • acts_upstream_of
      • involved_in
      • regulates
    • Decide on SOP for legacy annotations
      • This may be different for different annotation groups.
      • What would be involved in providing computational approaches to help curators?


Ontology editors

(Pascale) I have added labels to most issues: https://github.com/geneontology/go-ontology/labels

Topics:

  • 35 protein complex
  • 33 targeting and transport
  • 21 metabolism
  • 20 viruses and symbionts
  • 19 cellular processes
  • 19 enzymes
  • 19 development
  • 18 cell cycle and DNA processes
  • 16 neurobiology
  • 15 signaling
  • 13 binding
  • 11 transcription
  • 9 RNA processes
  • 8 regulation
  • 6 cell type
  • 5 synapse_project
  • 4 cellular component
  • 4 MF refactoring
  • 4 chromatin
  • 4 immune system
  • 4 multiorganism processes
  • 4 start_and_end
  • 4 translation
  • 3 miRNA
  • 3 required_for_LEGO
  • 2 compound terms
  • 2 fatty acid biosynthesis
  • 2 No_MF_in_GO
  • 2 toxin
  • 1 Cilia/flagella
  • 1 autophagy
  • 1 cardiac conduction
  • 1 Protein Complex WG
  • 1 recombination

Minutes

  • On call: