Ontology meeting 2020-12-14: Difference between revisions
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===Call next week? === | ===Call next week? === | ||
=== Compound Molecular Functions === | === (Compound) Molecular Functions === | ||
* Examples: | |||
** RNA helicase | |||
** Receptor | |||
** Signaling adaptors | |||
** Sequestering activities | |||
** http://noctua.geneontology.org/editor/graph/gomodel:5fb9cc0600000424 | |||
** http://noctua.geneontology.org/editor/graph/gomodel:584b49fa00000436 | |||
=== Cellular Component, ShEx, and GO-CAMs === | === Cellular Component, ShEx, and GO-CAMs === |
Revision as of 14:36, 10 December 2020
Present
Regrets:
Group members
Pascale, Karen, Harold, Peter, Jim, Tanya, Kimberly, David, Chris, Paul
Agenda
'process has causal agent' o 'in taxon' -> 'in taxon'
Proposed RO change https://github.com/oborel/obo-relations/pull/413
for GO issue https://github.com/geneontology/go-ontology/issues/17613
-> may not be acceptable
Sequence Ontology in go-lego (for Noctua)
https://github.com/geneontology/go-ontology/issues/20419
GitHub Discussions feature
https://docs.github.com/en/free-pro-team@latest/discussions
Call next week?
(Compound) Molecular Functions
- Examples:
- RNA helicase
- Receptor
- Signaling adaptors
- Sequestering activities
- http://noctua.geneontology.org/editor/graph/gomodel:5fb9cc0600000424
- http://noctua.geneontology.org/editor/graph/gomodel:584b49fa00000436
Cellular Component, ShEx, and GO-CAMs
- The ShEx specifications state that MFs can occur in an Anatomical Entity and that GPs or Protein-Containing Complexes can be located in an Anatomical Entity.
- Most non-protein-containing complex GO CC terms are a child of Cellular Anatomical Entity which is a subclass of Anatomical Entity.
- However, annotations to root Cellular Component result in ShEx violations because root Cellular Component is NOT a subclass of Anatomical Entity.
- How do we fix this?
- Change root Cellular Component annotations to Cellular Anatomical Entity (throughout GO)
- Change ShEx value to an OR statement, for example: MF occurs_in AnatomicalEntity OR CellularComponent
- Work on RO to see if there is a relation that could be used as a parent for all children of Cellular Component relations - overlaps?
- Take this issue to the RO call(s)?
- Move Protein-Containing Complex out of Cellular Component into its own GO aspect and make Cellular Component a subclass of Anatomical Entity
Other Business
https://github.com/geneontology/go-ontology/projects/1