PTHR10005: Difference between revisions
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**Summary of SF answer: No. See http://wiki.geneontology.org/index.php/Proposals_to_overhaul_transcription_in_GO_-_2010 for details. | **Summary of SF answer: No. See http://wiki.geneontology.org/index.php/Proposals_to_overhaul_transcription_in_GO_-_2010 for details. | ||
==Biological | ==Biological Process== | ||
*SF 3157237: I wonder why there are three independent pathways, BMP, SMAD and TGF signaling, that seem to be steps in the general TGF pathway - should there not be relationships between those terms? | *SF 3157237: I wonder why there are three independent pathways, BMP, SMAD and TGF signaling, that seem to be steps in the general TGF pathway - should there not be relationships between those terms? | ||
*#GO:0030509 : BMP signaling pathway | *#GO:0030509 : BMP signaling pathway | ||
Revision as of 15:37, 21 March 2011
This is a list of questions that arose while PAINTing PTHR10005.
Questions for MOD curators
Molecular Function
Mouse
- Question: Can you check histone deacetylase inhibitor activity IGI for the gene SKI? I would be OK with a regulation process, but not for a MF annotation from this paper. (via email 13 Jan 2011 - PG)
- Curator answer: Insert answer here.
Questions for ontology curators
Molecular Function
- SF 3157192: Why isn't GO:0003714 : transcription corepressor activity a GO:0030528 transcription regulator activity? Is this something that is planned?
- Summary of SF answer: No. See http://wiki.geneontology.org/index.php/Proposals_to_overhaul_transcription_in_GO_-_2010 for details.
Biological Process
- SF 3157237: I wonder why there are three independent pathways, BMP, SMAD and TGF signaling, that seem to be steps in the general TGF pathway - should there not be relationships between those terms?
- GO:0030509 : BMP signaling pathway
- GO:0007179 : transforming growth factor beta receptor signaling pathway
- GO:0060395 : SMAD protein signal transduction
- Summary of SF response:
- I've moved 'activin receptor activity ; GO:0017002' and its children out from under 'transforming growth factor beta receptor activity ; GO:0005024' to match the process terms.
- This means in GO, we are now consistently using TGF-beta to mean the molecule and not the superfamily.
- We'll go over the SMAD signaling in the workshop.