PTHR10146: Difference between revisions
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*'''Question: '''Please check if additional MF annotations could be made. This [http://journals.iucr.org/d/issues/2003/01/00/gr2282/gr2282.pdf paper], near the bottom of p. 132, says, 'Since three of the PLP-site interactions are the same for P007 and ARC, it was suspected that P007 may be an amino-acid racemase and accordingly it was tested for d-alanine racemase activity. Though it exhibited d- to l-alanine racemase activity, further tests are required to verify l- to d-alanine activity and to rule out other racemase activities.' | *'''Question: '''Please check if additional MF annotations could be made. This [http://journals.iucr.org/d/issues/2003/01/00/gr2282/gr2282.pdf paper], near the bottom of p. 132, says, 'Since three of the PLP-site interactions are the same for P007 and ARC, it was suspected that P007 may be an amino-acid racemase and accordingly it was tested for d-alanine racemase activity. Though it exhibited d- to l-alanine racemase activity, further tests are required to verify l- to d-alanine activity and to rule out other racemase activities.' | ||
**'''Curator | **'''Curator comment: '''"no data for the racemase activity and the authors do a lot of caveats about their statement." Seeking further advice. | ||
Revision as of 10:16, 22 March 2011
This is a list of questions that arose while PAINTing PTHR10146.
Questions for MOD curators
Molecular Function
SGD
- Question: Please check if additional MF annotations could be made. This paper, near the bottom of p. 132, says, 'Since three of the PLP-site interactions are the same for P007 and ARC, it was suspected that P007 may be an amino-acid racemase and accordingly it was tested for d-alanine racemase activity. Though it exhibited d- to l-alanine racemase activity, further tests are required to verify l- to d-alanine activity and to rule out other racemase activities.'
- Curator comment: "no data for the racemase activity and the authors do a lot of caveats about their statement." Seeking further advice.