Panther ID:11559

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General observation: There are a lot of annotations to "cytoplasm" (GO:0005737) and its children, but also to other non-cytoplasmic components of the cell. In this situation, I don't feel comfortable propagating "cytoplasm" annotations except in narrow circumstances, such as single clades.

Problems detected and fixed through annotation of this family:

• A link was added to make "ER lumen" (GO:0005788) an "ER part" (GO:0044432). (SF item 2828065) [1]
• (Pending) Several terms requested to be moved from children of "response to chemical stimulus" to "response to organic substance" (SF item 2830403) [2]