Procedure for selection of target genes (Retired): Difference between revisions
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* [http://www.ncbi.nlm.nih.gov/Omim/getmorbid.cgi OMIM Morbid Map] | * [http://www.ncbi.nlm.nih.gov/Omim/getmorbid.cgi OMIM Morbid Map] | ||
* [http://rgd.mcw.edu/dportal/ RGD disease portal] | * [http://rgd.mcw.edu/dportal/ RGD disease portal] | ||
* [http://www.genetests.org Gene Tests] | |||
* [http://www.pharmgkb.org/index.jsp PharmGKB] | * [http://www.pharmgkb.org/index.jsp PharmGKB] | ||
* [http://www.ogic.ca/projects/g2d_2/ G2D] | * [http://www.ogic.ca/projects/g2d_2/ G2D] |
Revision as of 16:01, 17 October 2007
Guidelines
- Try to select related genes (same pathway, same disease)
- Check that the gene is not already done (easiest to search by UniProt ID)
- Enter all ID in the Master Table
- For disease genes, enter the OMIM ID of the disease or a PMID of a paper describing the gene's implication in a disease
Disease genes
Conserved Human-E.coli
- list of genes is in the 'Suggestions' spreadsheet (look for the "conserved Hs-Ec" sheet)
- enter the ensemble ID in YOGY
- find the UniProt ID from the YOGY summary tables
- check the 'master list' to make sure the gene has not previously been selected
Bleeding edge genes
- Recent highlighted articles in your database
- Science Daily
- Medline
- Expasy Spotlight
- other suggestions welcome
Biochemical/signaling pathways
Try picking 5 genes form the same pathway