Procedure for selection of target genes (Retired): Difference between revisions

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# Enter all ID in the [http://spreadsheets0.google.com/ccc?key=pwOksMOra5uq4vIYjPgefPw Master Table]. The Human Genome Nomenclature Committee's site is a nice source for those IDs, [http://www.genenames.org/cgi-bin/hgnc_search.pl HGNC search tool].
# Enter all ID in the [http://spreadsheets0.google.com/ccc?key=pwOksMOra5uq4vIYjPgefPw Master Table]. The Human Genome Nomenclature Committee's site is a nice source for those IDs, [http://www.genenames.org/cgi-bin/hgnc_search.pl HGNC search tool].
# For disease genes, enter the OMIM ID of the disease or a PMID of a paper describing the gene's implication in a disease
# For disease genes, enter the OMIM ID of the disease or a PMID of a paper describing the gene's implication in a disease
# This site is pretty useful for finding all of the identifiers that go in the various columns [http://www.genenames.org/cgi-bin/hgnc_search.pl HGNC Search]


== Disease genes ==
== Disease genes ==

Revision as of 16:37, 23 October 2007

Guidelines

  1. Try to select related genes (same pathway, same disease)
  2. Check that the gene is not already done (easiest to search by UniProt ID)
  3. Enter all ID in the Master Table. The Human Genome Nomenclature Committee's site is a nice source for those IDs, HGNC search tool.
  4. For disease genes, enter the OMIM ID of the disease or a PMID of a paper describing the gene's implication in a disease
  5. This site is pretty useful for finding all of the identifiers that go in the various columns HGNC Search

Disease genes

Conserved Human-E.coli

  • list of genes is in the 'Suggestions' spreadsheet (look for the "conserved Hs-Ec" sheet)
  • enter the ensemble ID in YOGY
  • find the UniProt ID from the YOGY summary tables
  • check the 'master list' to make sure the gene has not previously been selected

Bleeding edge genes

Biochemical/signaling pathways

Try picking 5 genes form the same pathway