Procedure for selection of target genes (Retired): Difference between revisions
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* [http://www.ogic.ca/projects/g2d_2/ G2D] | * [http://www.ogic.ca/projects/g2d_2/ G2D] | ||
* [http://superfly.ucsd.edu/homophila/ Drosophila & human disease] | * [http://superfly.ucsd.edu/homophila/ Drosophila & human disease] | ||
* Search GoogleNews for "genes" [http://news.google.com/news?hl=en&ned=us&q=genes&btnG=Search+News] | |||
== Conserved Human-E.coli == | == Conserved Human-E.coli == |
Revision as of 12:13, 27 October 2007
Guidelines
- Try to select related genes (same pathway, same disease)
- Check that the gene is not already done (easiest to search by UniProt ID)
- Enter all ID in the Master Table. The Human Genome Nomenclature Committee's site is a nice source for those IDs, HGNC search tool.
- For disease genes, enter the OMIM ID of the disease or a PMID of a paper describing the gene's implication in a disease
- This site is pretty useful for finding all of the identifiers that go in the various columns HGNC Search
Disease genes
- OMIM Morbid Map
- RGD disease portal
- Gene Tests
- PharmGKB
- G2D
- Drosophila & human disease
- Search GoogleNews for "genes" [1]
Conserved Human-E.coli
- list of genes is in the 'Suggestions' spreadsheet (look for the "conserved Hs-Ec" sheet)
- enter the ensemble ID in YOGY
- find the UniProt ID from the YOGY summary tables
- check the 'master list' to make sure the gene has not previously been selected
Bleeding edge genes
- Recent highlighted articles in your database
- Science Daily
- Medline
- AAAS's EurekAlert
- Expasy Spotlight
- other suggestions welcome
Biochemical/signaling pathways
Try picking 5 genes form the same pathway