Procedure for selection of target genes (Retired): Difference between revisions

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==Rotation Order==
This is the list of which group is responsible for selecting curation targets for the next year:
* November 2007: Arabidopsis thaliana
* December 2007: Caenorhabditis elegans
* January 2008: Danio rerio
* February 2008: Dictyostelium discoideum
* March 2008: Drosophila melanogaster
* April 2008: Escherichia coli
* May 2008: Gallus gallus
* June 2008: Homo sapiens
* July 2008: Mus musculus
* August 2008: Rattus norvegicus
* September 2008: Saccharomyces cerevisiae
* October 2008: Schizosaccharomyces pombe
== Guidelines ==
== Guidelines ==
# Try to select related genes (same pathway, same disease)
# Try to select related genes (same pathway, same disease)

Revision as of 15:41, 2 November 2007

Rotation Order

This is the list of which group is responsible for selecting curation targets for the next year:

  • November 2007: Arabidopsis thaliana
  • December 2007: Caenorhabditis elegans
  • January 2008: Danio rerio
  • February 2008: Dictyostelium discoideum
  • March 2008: Drosophila melanogaster
  • April 2008: Escherichia coli
  • May 2008: Gallus gallus
  • June 2008: Homo sapiens
  • July 2008: Mus musculus
  • August 2008: Rattus norvegicus
  • September 2008: Saccharomyces cerevisiae
  • October 2008: Schizosaccharomyces pombe


Guidelines

  1. Try to select related genes (same pathway, same disease)
  2. Check that the gene is not already done (easiest to search by UniProt ID)
  3. Enter all ID in the Master Table. The Human Genome Nomenclature Committee's site is a nice source for those IDs, HGNC search tool.
  4. For disease genes, enter the OMIM ID of the disease or a PMID of a paper describing the gene's implication in a disease
  5. This site is pretty useful for finding all of the identifiers that go in the various columns HGNC Search

Disease genes

Conserved Human-E.coli

  • list of genes is in the 'Suggestions' spreadsheet (look for the "conserved Hs-Ec" sheet)
  • enter the ensemble ID in YOGY
  • find the UniProt ID from the YOGY summary tables
  • check the 'master list' to make sure the gene has not previously been selected

Bleeding edge genes

Biochemical/signaling pathways

Try picking 5 genes form the same pathway