Protein complexes
- This is a work in progress. Also, we need to add examples - what works and what doesn't.
- How do we view protein complexes in GO. The complex should be stable. If not stable, it's just protein binding. I'm sure we had something written down for this - Birgit? Do GO and IntAct guidelines agree on this.
- GO should host species-agnostic complexes, ideally conserved across taxa. Where this isn't known, still make the def generic, and add 'For example, in human this complex contains...' as a def gloss or def comment. Species-specific complexes don't belong in GO, but rather in IntAct and/or PRO (or just IntAct?).
- Ideally, add capable_of functions link. If not possible, see if capable_of_part_of process links can be made. If none is applicable, we do host complexes based on their subunits only.
- Indicate cellular location as specifically as possible, unless parent already has one
- How to request protein complexes in GO based on the above (TG template, TG freeform)
- Emily started documentation here, in case it's helpful, but this wasn't worked on since 2011: http://wiki.geneontology.org/index.php/Protein_Complex_ids_as_GO_annotation_objects