Provides input for: Difference between revisions
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*'provides input for' should be reserved to related successive Molecular Functions in GO-CAM models. | *'provides input for' should be reserved to related successive Molecular Functions in GO-CAM models. | ||
**Usage Examples | **Usage Examples | ||
***In glycolysis, triose phosphate isomerase activity (MF) ' | ***In glycolysis, triose phosphate isomerase activity (MF) 'provides input for' glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (MF). | ||
**** triose phosphate isomerase activity converts dihydroxyacetone phosphate (input) to glyceraldehyde-3-phosphate (output) as part of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase converts glyceraldehyde-3-phosphate (input) to 3-phosphonato-D-glyceroyl phosphate(4−) (output). | **** triose phosphate isomerase activity converts dihydroxyacetone phosphate (input) to glyceraldehyde-3-phosphate (output) as part of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase converts glyceraldehyde-3-phosphate (input) to 3-phosphonato-D-glyceroyl phosphate(4−) (output). | ||
****http://noctua.geneontology.org/editor/graph/gomodel:632cf60a00000208 | ****http://noctua.geneontology.org/editor/graph/gomodel:632cf60a00000208 |
Revision as of 05:10, 8 February 2023
Overview and Scope of Use
- This relation is used in GO-CAMs but not in standard annotation extensions.
- This relation is intended to connect successive enzymatic reactions in a pathway, i.e. where the product (output) of the upstream activity is the substrate (input) for the downstream activity.
- When the output molecule of the upstream activity is available in ChEBI, curators should not use this relation, and should instead connect the successive activities via the output molecule: [upstream] has_output [ChEBI] is_input [downstream].
- When the output molecule is not available (usually a modified protein or RNA), use: [upstream] provides_input_for [downstream].
- The 'provides input for' relation is used to relate two GO Molecular Functions when:
- Two Molecular Functions succeed one another directly
- The output of the first molecular function is an input of the second Molecular Function.
- The output of the first molecular function is not available in ChEBI.
Annotation Usage Guidelines
- 'provides input for' should be reserved to related successive Molecular Functions in GO-CAM models.
- Usage Examples
- In glycolysis, triose phosphate isomerase activity (MF) 'provides input for' glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (MF).
- triose phosphate isomerase activity converts dihydroxyacetone phosphate (input) to glyceraldehyde-3-phosphate (output) as part of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase converts glyceraldehyde-3-phosphate (input) to 3-phosphonato-D-glyceroyl phosphate(4−) (output).
- http://noctua.geneontology.org/editor/graph/gomodel:632cf60a00000208
- A glucose tansmembrane transporter activity (MF) 'directly provides input for' lactose synthase activity (MF).
- cytosolic glucose (input) is transported across the Golgi membrane to become Golgi-lumenal glucose (output). In the Golgi lumen the Golgi-lumenal glucose (input) is converted into lactose (output).
- http://noctua.geneontology.org/editor/graph/gomodel:632cf60a00000239?
- In glycolysis, triose phosphate isomerase activity (MF) 'provides input for' glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (MF).
- Usage Examples
Ontology Usage Guidelines
- This relation is not used in the ontology.
Cross Reference to the Relation Ontology (RO)
Review Status
Reviewed: Nov 2, 2022 DavidH