Reference Genome Annotation Meeting

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General Info

The first Reference Genome annotation Meeting will be held (tentatively) September 26-27, 2007 in Princeton, NJ, right after the GO consortium and GO advisors meeting.

Agenda

Strategies to identify orthologs

  • Procedures different databases are using can be found on the Orthology discussion page
  • Standardize procedure for identification across MODs
  • Which model organisms are available in which databases, e.g. Dicty is not in Treefam; zebra fish & chicken are not in YOGY

How to prioritize disease genes


How to assess the progress made towards curation of reference genome genes; strategies for improvement


Review of progress toward database and tool development

  • Chris, Sohel and Mary are developing a web-based tool that will replace the currant Google spreadsheet
  • Demonstration of the tool (link to a page with the tool coming soon)
  • Curator input for further development

Discussions regarding metrics, including making a plan for how to use metrics

  • Integrating both functional and structural information into the metrics we develop. How are we going to integrate sequence into this pipeline?
  • Each reference genome must provide its sequence as GFF3 file [Karen Eilbeck]

Annotation consistency exercises