Signaling ontology structure documentation

Top categories

[i]signaling systems grouped by chemical properties of the signal 
---[i]hydrophobic molecule-mediated signaling 
---[i]hydrophilic molecule-mediated signaling 
---[i]intracellular signaling
------[i]large intracellular mloecule-mediated signaling
---[i]intercellular signaling

[i]signaling systems grouped by outcome of the signal
---[i]signaling to control gene expression


[i]long distance signaling
[i]short distance signaling

[i]molecular switch-like signaling
---[i]phosphoylation/dephosphorylation-mediated signaling
---[i]GTP-binding protein-mediated signaling

Sub-groups

[i]hydrophobic molecule-mediated signaling 
---[i]nitrous oxide-mediated signaling
---[i]carbon monoxide-mediated signaling

[i]hydrophilic molecule-mediated signaling 

[i]signaling to control gene expression
---[i]primary response
---[i]secondary response

//distance is going to be problematic but this is how the book defines them. Also tricky between plants and animals.

[i]long distance signaling
---[i]long distance hormone-mediated signaling
---[i]long distance nervous system-mediated signaling

[i]short distance signaling
---[i]local mediators (paracrine signaling)

//large and small moleculaes are also going to be difficult.

[i]large intracellular mloecule-mediated signaling
---[i]relay protein-mediated signaling
---[i]messenger protein-mediated signaling
---[i]adaptor protein-mediated signaling
---[i]amplifier protein-mediated signaling
---[i]transducer protein-mediated signaling
---[i]bifurcation protein-mediated signaling
---[i]integrator protein-mediated signaling
---[i]latent gene regulatory protein-mediated signaling