SourceForge meeting 2014-05-14

Do we need a separate 'multicellular organism senescence' term, or does 'multicellular organismal aging' suffice?

PO need this term for defining some of their processes e.g. 4 leaf senescence stage ; PO:0001054. This is the ticket: https://sourceforge.net/p/geneontology/ontology-requests/10381/

Boundaries of protein complex:

This ticket requires deciding whether spindles are protein complexes:

https://sourceforge.net/p/geneontology/ontology-requests/10824/

'protein complex' currently has the def: "Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules."

Can we tighten up the definition to make clear what components are allowed. How about:

"Any macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccaride) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical."

?

Note - centrosome part of spindle & centrosome *may* have other components besides protein: http://download.springer.com/static/pdf/10/art%253A10.1007%252Fs10577-011-9186-7.pdf?auth66=1400247153_36a440116ffd10fb172a63495c67c10a&ext=.pdf