Talk:2010 GO camp Annotation of complexes issues: Difference between revisions

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GO: Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.  
GO: Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.  


**  Q: do transient complexes qualify?  
Q: do transient complexes qualify? <br>
 
A: grey area- for example cdk/cyclin is considered a complex; rather a case-by case basis
A: grey area- for example cdk/cyclin is considered a complex; rather a case-by case basis


** Q: How are different species captured?  
Q: How are different species captured? <br>
 
A: right now all spp are kept separate; look for experimental support for the complex. NOT propagating complexes.
A: right now all spp are kept separate; look for experimental support for the complex. NOT propagating complexes.

Revision as of 09:19, 27 April 2010

  • Could we possibly use IntAct to perform annotations

IntAct: a complex is something that can be purified , ideally has a function
GO: Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.

Q: do transient complexes qualify?
A: grey area- for example cdk/cyclin is considered a complex; rather a case-by case basis

Q: How are different species captured?
A: right now all spp are kept separate; look for experimental support for the complex. NOT propagating complexes.