Talk:2010 GO camp Annotation of complexes issues: Difference between revisions
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A: (Emily):<br> | A: (Emily):<br> | ||
A: (Sandra) | A: (Sandra) | ||
Q: Will IntAct be able to support all MODs? | |||
Q: Are there other resources we should be looking into? |
Revision as of 09:31, 27 April 2010
- Could we possibly use IntAct to perform annotations ?
IntAct: a complex is something that can be purified , ideally has a function
GO: Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.
Q: do transient complexes qualify?
A: (Sandra) grey area- for example cdk/cyclin is considered a complex; rather a case-by case basis
Q: How are different species captured?
A: (Sandra) right now all spp are kept separate; look for experimental support for the complex. NOT propagating complexes.
Q: If we annotate to complexes, how will we annotate the individual subunits to the MF/BP?
A: (Emily):
A: (Sandra)
Q: Will IntAct be able to support all MODs?
Q: Are there other resources we should be looking into?